KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TH
All Species:
27.58
Human Site:
S386
Identified Species:
46.67
UniProt:
P07101
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07101
NP_000351.2
528
58600
S386
S
Q
D
I
G
L
A
S
L
G
A
S
D
E
E
Chimpanzee
Pan troglodytes
XP_508221
618
67613
S476
S
Q
D
I
G
L
A
S
L
G
A
S
D
E
E
Rhesus Macaque
Macaca mulatta
Q2HZ26
490
56076
Q352
G
A
S
D
E
D
V
Q
K
L
A
T
C
Y
F
Dog
Lupus familis
XP_855547
495
55650
A356
I
G
L
A
S
L
G
A
S
D
E
E
I
E
K
Cat
Felis silvestris
Mouse
Mus musculus
P24529
498
55975
S356
S
Q
D
I
G
L
A
S
L
G
A
S
D
E
E
Rat
Rattus norvegicus
P04177
498
55948
S356
S
Q
D
I
G
L
A
S
L
G
A
S
D
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507458
568
65241
S426
S
Q
E
I
G
L
A
S
L
G
A
P
D
E
Y
Chicken
Gallus gallus
P70080
445
51121
Q307
G
A
S
D
E
A
V
Q
K
L
A
T
C
Y
F
Frog
Xenopus laevis
Q92142
481
55388
Q343
G
A
S
D
E
A
V
Q
K
L
A
T
C
Y
F
Zebra Danio
Brachydanio rerio
NP_571224
489
55584
S351
G
L
A
S
L
G
A
S
D
E
D
I
E
K
L
Tiger Blowfish
Takifugu rubipres
NP_001027874
476
54285
E338
A
S
L
G
V
S
D
E
D
I
E
K
L
S
T
Fruit Fly
Dros. melanogaster
P18459
579
65977
S434
S
Q
E
I
G
L
A
S
L
G
A
S
D
E
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P90925
457
52111
E319
G
A
P
D
D
V
I
E
K
L
A
T
L
Y
W
Sea Urchin
Strong. purpuratus
XP_786206
522
59629
S380
S
Q
E
I
G
L
A
S
L
G
V
A
D
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.1
43.1
84.2
N.A.
83.3
84.2
N.A.
45
43.7
42.9
65.1
51.8
43.1
N.A.
40.7
46.7
Protein Similarity:
100
83.6
60
87.5
N.A.
86.9
87.8
N.A.
60.3
58.7
60.2
77.6
66.8
61.4
N.A.
59.2
65.7
P-Site Identity:
100
100
6.6
13.3
N.A.
100
100
N.A.
80
6.6
6.6
13.3
0
93.3
N.A.
6.6
73.3
P-Site Similarity:
100
100
13.3
26.6
N.A.
100
100
N.A.
86.6
13.3
13.3
26.6
6.6
100
N.A.
20
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
29
8
8
0
15
58
8
0
0
72
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
22
0
0
% C
% Asp:
0
0
29
29
8
8
8
0
15
8
8
0
50
0
8
% D
% Glu:
0
0
22
0
22
0
0
15
0
8
15
8
8
58
36
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
22
% F
% Gly:
36
8
0
8
50
8
8
0
0
50
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
50
0
0
8
0
0
8
0
8
8
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
29
0
0
8
0
8
8
% K
% Leu:
0
8
15
0
8
58
0
0
50
29
0
0
15
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
50
0
0
0
0
0
22
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
50
8
22
8
8
8
0
58
8
0
0
36
0
8
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
29
0
0
8
% T
% Val:
0
0
0
0
8
8
22
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
29
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _